89-7769-63 Recombinant Human PROC1/Protein C/PROC Protein (His Tag) 20ug PKSH031776
[Elabscience]
特徴
- 背景：CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：(79+20.5) % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：P04070
- タグ種類：C-His
- アミノ酸配列：Met 1-Pro461
- 遺伝子構造：A DNA sequence encoding the human PROC (P04070) (Met1-Pro461) was expressed with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：APC;PC;PROC;PROC1;THPH3;THPH4
- 分子量：51.5 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38169-Elabscience-PKSH031776.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7769-62
Recombinant Human PROC1/Protein C/PROC Protein (His Tag) 10ug
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89-7769-63
Recombinant Human PROC1/Protein C/PROC Protein (His Tag) 20ug
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