89-7768-65 ［取扱停止］Recombinant Human CD32b/FCGR2B Protein (HEK293 Cells, His Tag)(Active) 50ug PKSH031726
[Elabscience]
特徴
- 背景：Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_001002274.1
- タグ種類：C-His
- アミノ酸配列：Ala 46-Pro 217
- 遺伝子構造：A DNA sequence encoding the extracellular domain (Ala 46-Pro 217) of mature human CD32b (NP_001002274.1) protein was expressed with a N-terminal signal peptide and a C-terminal polyhistidine tag.
- 活性：Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD32b at 10 μg/ml (100 μl/well) can bind human IgG2 with a linear range of 0.16-6.4 μg/ml.
- 別名（遺伝子名）：Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; Fc-Gamma RII-b; Fc-Gamma-RIIb; FcRII-b; CD32; FCGR2B; FCG2; IGFR2
- 分子量：20.8 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105712-Elabscience-PKSH031726.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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89-7768-66
Recombinant Human CD32b/FCGR2B Protein (HEK293 Cells, His Tag)(Active) 100ug
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89-7768-65
Recombinant Human CD32b/FCGR2B Protein (HEK293 Cells, His Tag)(Active) 50ug
|
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