89-7768-52 Recombinant Human OMGP/OMG Protein (aa 1-416, His Tag)(Active) 100ug PKSH031718
[Elabscience]
特徴
- 背景：Oligodendrocyte-myelin glycoprotein; also known as OMG and OMGP; is a cell membrane protein which contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR; the receptor for Nogo. This function requires its leucine-rich repeat domain; a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation; neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P23515-1
- タグ種類：C-His
- アミノ酸配列：Met 1-Pro 416
- 遺伝子構造：A DNA sequence encoding the mature form of human OMGP (P23515-1) (Met 1-Pro 416) without the pro peptide was expressed; fused with a polyhistidine tag at the C-terminus.
- 活性：Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. Immobilized OMG (0.8 μg/ml; 100 μl/well) will mediate >15% C6 cell adhesion.
- 別名（遺伝子名）：OMGP
- 分子量：46 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105707-Elabscience-PKSH031718.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7768-51
Recombinant Human OMGP/OMG Protein (aa 1-416, His Tag)(Active) 20ug
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89-7768-52
Recombinant Human OMGP/OMG Protein (aa 1-416, His Tag)(Active) 100ug
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