89-7767-53 ［取扱停止］Recombinant Human SLPI Protein (aa 26-132, His Tag)(Active) 200ug PKSH031666
[Elabscience]
特徴
- 背景：Secretory leukoprotease inhibitor (SLPI); also called antileukoprotease (ALP); is a 12-kDa; nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in protecting the mucosae from injury associated with inflammation. SLPI is locally produced by serous cells; including bronchial submucosal glands. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites; and have been shown to be modulated in multiple pathological conditions. Elafin and SLPI are structurally related in that both have a fold with a four-disulfide core or whey acidic protein (WAP) domain responsible for inhibiting proteases. SLPI is a prominent innate immune protein of the respiratory tract; possessing serine protease inhibitor activity; antibacterial activity; and anti-inflammatory/immunomodulatory activity.
仕様
- サイズ：200ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 84 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P03973
- タグ種類：N-His
- アミノ酸配列：Ser 26-Ala 132
- 遺伝子構造：A DNA sequence encoding the secreted form of human SLPI (P03973) (Ser 26-Ala 132) was expressed; with a polyhistidine tag at the N-terminus.
- 活性：Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate; Mca-RPKPVE-Nval-WRK (Dnp)-NH2 (Catalog # ES002).The IC50 value is <4 Nm.
- 別名（遺伝子名）：ALK1;ALP;BLPI;HUSI;HUSI-I;MPI;WAP4;WFDC4
- 分子量：14 kDa
- 組成：Lyophilized from sterile 20mM Tris; 500mM NaCl; pH 7.4; 10% gly
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105692-Elabscience-PKSH031666.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7767-53
Recombinant Human SLPI Protein (aa 26-132, His Tag)(Active) 200ug
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89-7767-52
Recombinant Human SLPI Protein (aa 26-132, His Tag)(Active) 100ug
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