89-7767-16 ［取扱停止］Recombinant Human MOG Protein (aa 30-149, His Tag) 20ug PKSH031647
[Elabscience]
特徴
- 背景：Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_996532.2
- タグ種類：C-His
- アミノ酸配列：Gly 30-Tyr 149
- 遺伝子構造：A DNA sequence encoding the extracellular domain of human MOG (NP_996532.2) (Gly 30-Tyr 149) was expressed, fused with a polyhistidine tag at the C-terminus and an additional Met at the N-terminus.
- 別名（遺伝子名）：Myelin-Oligodendrocyte Glycoprotein; MOG;BTN6;BTNL11;MOGIG2;NRCLP7
- 分子量：15 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105687-Elabscience-PKSH031647.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7767-16
Recombinant Human MOG Protein (aa 30-149, His Tag) 20ug
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89-7767-17
Recombinant Human MOG Protein (aa 30-149, His Tag) 50ug
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