89-7764-92 Recombinant Human CD226/DNAM-1 Protein (His Tag)(Active) 100ug PKSH031523
[Elabscience]
特徴
- 背景：The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226; also known as PTA1 or DNAM-1; is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells; platelets; monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.Immune CheckpointImmune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: FCM AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_006557.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Asn 247
- 遺伝子構造：A DNA sequence encoding the human DNAM1 (NP_006557.2) extracellular domain (Met 1-Asn 247) was fused with a polyhistidine tag at the C-terminus.
- 活性：Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μl/well) can bind human CD112 with a linear ranger of 6.4-800 ng/ml.
- 別名（遺伝子名）：DNAM-1;DNAM1;PTA1;TLiSA1
- 分子量：27.6 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105655-Elabscience-PKSH031523.pdf
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89-7764-92
Recombinant Human CD226/DNAM-1 Protein (His Tag)(Active) 100ug
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89-7764-91
Recombinant Human CD226/DNAM-1 Protein (His Tag)(Active) 50ug
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