特徴
- 背景:Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:NP_003271.1
- アミノ酸配列:Met 1-Glu161
- 遺伝子構造:A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified.
- 別名(遺伝子名):CMD1Z;CMH13;TN-C;TNC;TNNC
- 分子量:18.4 kDa
- 組成:Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-37846-Elabscience-PKSH031309.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7761-12
Recombinant Human Troponin C/TNNC1 Protein 20ug
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89-7761-13
Recombinant Human Troponin C/TNNC1 Protein 100ug
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