89-7760-95 ［取扱停止］Recombinant Human IL-22BP/IL22RA2 Protein (His & Fc Tag) 20ug PKSH031301
[Elabscience]
特徴
- 背景：Interleukin-22 receptor subunit alpha-2 (IL-22RA2); also known as interleukin-22-binding protein (IL-22BP); is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type I I cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues; including those in the digestive; female reproductive; and immune systems. It is expressed in placenta; spleen; breast; skin and lung. It is also detected in intestinal tract; testis; brain; heart and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important roles in immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptor have been discovered; a membrane-bound receptor and a soluble receptor.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_851826.1
- タグ種類：C-His & Fc
- アミノ酸配列：Met 1-Pro 231
- 遺伝子構造：A DNA sequence encoding the human IL22RA2 isoform 2 (NP_851826.1) (Met 1-Pro 231) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：CRF2-10;CRF2-S1;CRF2X;IL-22BP;IL-22R-alpha-2;IL-22RA2;ZCYTOR16
- 分子量：52.8 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37840-Elabscience-PKSH031301.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7760-95
Recombinant Human IL-22BP/IL22RA2 Protein (His & Fc Tag) 20ug
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89-7760-96
Recombinant Human IL-22BP/IL22RA2 Protein (His & Fc Tag) 50ug
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