89-7759-33 Recombinant Human SETD7/SET7/9 Protein (His Tag) 100ug PKSH031208
[Elabscience]
特徴
- 背景：Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysine methyltransferase (PKMT), SETD7 also has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding in substrate proteins. The mono-methyltransferase activity of SETD7 is achieved by disrupting the formation at near-attack conformations for the dimethylation reaction. SETD7 is also a novel coactivator of NF-kappaB and plays a role in inflammation and diabetes.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 94 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_085151.1
- タグ種類：N-His
- アミノ酸配列：Asp 2-Lys 366
- 遺伝子構造：A DNA sequence encoding the human SETD7 (NP_085151.1) (Asp 2-Lys 366) was expressed, with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：KMT7;SET7;SET7/9;SET9
- 分子量：41.5 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37775-Elabscience-PKSH031208.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7759-32
Recombinant Human SETD7/SET7/9 Protein (His Tag) 20ug
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89-7759-33
Recombinant Human SETD7/SET7/9 Protein (His Tag) 100ug
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