89-7758-57 ［取扱停止］Recombinant Human AKR1B1 Protein (His Tag) 50ug PKSH031165
[Elabscience]
特徴
- 背景：Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the collecting tubule cells and thought to provide protection against hypertonic environment. Some human tissues contain AKR1B1 as well as AKR1B10, a closely related member of the aldo-keto reductase superfamily.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P15121
- タグ種類：N-His
- アミノ酸配列：Met 1-Phe 316
- 遺伝子構造：A DNA sequence encoding the human AKR1B1 (P15121) (Met 1-Phe 316) was expressed, with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：ADR;ALDR1;ALR2;AR;MGC1804
- 分子量：37.9 kDa
- 組成：Lyophilized from sterile PBS, 20% glycerol, pH 7.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105550-Elabscience-PKSH031165.pdf
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89-7758-58
Recombinant Human AKR1B1 Protein (His Tag) 100ug
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89-7758-57
Recombinant Human AKR1B1 Protein (His Tag) 50ug
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