89-7757-89 Recombinant Human SULT2B1 Protein (aa 2-365, His Tag) 50ug PKSH031127
[Elabscience]特徴
- 背景:Sulfotransferase family cytosolic 2B member 1; also known as Sulfotransferase 2B1; ST2B1; Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2; SULT2B1 and HSST2; is a cytoplasm protein which belongs to the sulfotransferase 1 family. The human hydroxysteroid sulfotransferase (SULT) family is comprised of two subfamilies; SULT2A1 and SULT2B1. SULT2B1 is expressed highly in placenta; prostate and trachea. A lesser expression of SULT1B1 was observed in the small intestine and lung. SULT2B1 catalyzes the sulfate conjugation of many hormones; neurotransmitters; drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds; and therefore their renal excretion; but it can also result in bioactivation to form active metabolites. SULT2B1 sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol. The two SULT2B1 isoforms; SULT2B1a and SULT2B1b; are encoded by a single gene as a result of alternative transcription initiation and alternative splicing. SULT2B1b catalyzes the sulfonation of 3beta-hydroxysteroid hormones and cholesterol; whereas SULT2B1a preferentially catalyzes pregnenolone sulfonation.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 76 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:NP_004596.2
- タグ種類:N-His
- アミノ酸配列:Asp 2-Ser 365
- 遺伝子構造:A DNA sequence encoding the human SULT2B1 (NP_004596.2) (Asp 2-Ser 365) was expressed; with a N-terminal polyhistidine tag.
- 別名(遺伝子名):Sulfotransferase Family Cytosolic 2B Member 1; ST2B1; Sulfotransferase 2B1; Alcohol Sulfotransferase; Hydroxysteroid Sulfotransferase 2; SULT2B1; HSST2
- 分子量:42 kDa
- 組成:Lyophilized from sterile 20mM Tris; 0.1M NaCl; 10% glycerol; pH 8.0
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-37712-Elabscience-PKSH031127.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7757-88
Recombinant Human SULT2B1 Protein (aa 2-365, His Tag) 20ug
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89-7757-89
Recombinant Human SULT2B1 Protein (aa 2-365, His Tag) 50ug
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