特徴
- 背景:Ubiquitin-conjugating enzyme E2 D1 (UBE2D1); a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P51668
- タグ種類:N-His
- アミノ酸配列:Ala 2-Met 147
- 遺伝子構造:A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed; with a polyhistide tag at the N-terminus.
- 別名(遺伝子名):Ubiquitin-conjugating enzyme E2 D1;Stimulator of Fe transport;SFT;UBC4/5 homolog;UbcH5;Ubiquitin carrier protein D1;Ubiquitin-conjugating enzyme E2(17)KB 1;Ubiquitin-conjugating enzyme E2-17 kDa 1;Ubiquitin-protein ligase D1;SFT; UBC5A; UBCH5; UBCH5A
- 分子量:18.3 kDa
- 組成:Lyophilized from sterile 25mM Tris; 100mM NaCl; 20% glycerol; 0.05% Tween
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-37711-Elabscience-PKSH031122.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7757-82
Recombinant Human UBE2D1 Protein (His Tag) 50ug
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89-7757-83
Recombinant Human UBE2D1 Protein (His Tag) 100ug
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