89-7757-56 ［取扱停止］Recombinant Human Coagulation Factor IX/F9 Protein (His Tag)(Active) 20ug PKSH031109
[Elabscience]
特徴
- 背景：Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：AAB59620.1
- タグ種類：C-His
- アミノ酸配列：Met 1-Thr 461
- 遺伝子構造：A DNA sequence encoding the human F9 (AAB59620.1) (Met 1-Thr 461) was expressed, fused with a polyhistidine tag at the C-terminus.
- 活性：Measured by its ability to cleave the peptide substrate, Z-D-Arg-Gly-Arg-pNA. The specific activity is >20pmols/min/ug.
- 別名（遺伝子名）：Coagulation factor 9;F9;Coagulation factor IX;Christmas factor;Plasma thromboplastin component;Coagulation factor IXa light chain;Coagulation factor IXa heavy chain;FIX;HEMB;P19;PTC;THPH8
- 分子量：50 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37702-Elabscience-PKSH031109.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7757-57
Recombinant Human Coagulation Factor IX/F9 Protein (His Tag)(Active) 50ug
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89-7757-56
Recombinant Human Coagulation Factor IX/F9 Protein (His Tag)(Active) 20ug
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