89-7757-35 ［取扱停止］Recombinant Human NCR2/NKp44/CD336 Protein (His Tag) 100ug PKSH031094
[Elabscience]
特徴
- 背景：Natural cytotoxicity triggering receptor 2 (NCR2), also known as Natural killer cell p44-related protein (NKp44), or CD336, is a member of the natural cytotoxicity receptor (NCR) family, which composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. It is a novel transmembrane glycoprotein belonging to the Immunoglobulin superfamily characterized by a single extracellular V-type domain. The cytoplasmic domain of NKp44 also contains a sequence that matches the immunoreceptor tyrosine-based inhibitory motif (ITIM) consensus. This Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp44 is selectively expressed by IL-2-activated NK cells and may contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis. Tumor cell recognition of the mutated NKp44 proteins was significantly reduced and correlated with their lower recognition of heparin.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 88 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_004819.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Pro 190
- 遺伝子構造：A DNA sequence encoding the human NCR2 (NP_004819.2) extracellular domain (Met 1-Pro 190) was fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：CD336;dJ149M18.1;LY95;NK-p44;NKP44;RP1-149M18.2
- 分子量：20 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37691-Elabscience-PKSH031094.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7757-34
Recombinant Human NCR2/NKp44/CD336 Protein (His Tag) 50ug
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89-7757-35
Recombinant Human NCR2/NKp44/CD336 Protein (His Tag) 100ug
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