89-7757-01 Recombinant Human SULT1B1 Protein (His Tag)(Active) 50ug PKSH031074
[Elabscience]
特徴
- 背景：Sulfotransferase family cytosolic 1B member 1; also known as Sulfotransferase 1B1; Sulfotransferase 1B2; Thyroid hormone sulfotransferase; SULT1B1 and ST1B2; is a cytoplasm protein which belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones; neurotransmitters; drugs; and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1B1 is highly expressed in the liver; peripheral blood leukocytes; colon (mucosal lining); small intestine (jejunum) and spleen. A lesser expression of SULT1B1 was observed in the lung; placenta and thymus. SULT1B1 catalyzes the sulfate conjugation of many hormones; neurotransmitters; drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds; and therefore their renal excretion; but it can also result in bioactivation to form active metabolites. SULT1B1 sulfates dopamine; small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones; including 3;3'-diiodothyronine; triidothyronine; reverse triiodothyronine and thyroxine.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_055280.2
- タグ種類：N-His
- アミノ酸配列：Leu 2-Ile 296
- 遺伝子構造：A DNA sequence encoding the human SULT1B1 (NP_055280.2) (Leu 2-Ile 296) was expressed; with a N-terminal polyhistidine tag.
- 活性：Measured by its ability to transfer sulfate from PAPS to 1-Napthol.The specific activity is > 40 pmoles/min/μg.
- 別名（遺伝子名）：Sulfotransferase Family Cytosolic 1B Member 1; ST1B1; Sulfotransferase 1B1; Sulfotransferase 1B2; ST1B2; Thyroid Hormone Sulfotransferase; SULT1B1; ST1B2; SULT1B2
- 分子量：35.7 kDa
- 組成：Lyophilized from sterile 20mM Tris; 0.1 M NaCl; 10% glycerol; 1mM DTT; pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37673-Elabscience-PKSH031074.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7756-99
Recombinant Human SULT1B1 Protein (His Tag)(Active) 20ug
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89-7757-01
Recombinant Human SULT1B1 Protein (His Tag)(Active) 50ug
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