89-7756-95 ［取扱停止］Recombinant Human ATF2 Protein (His & GST Tag) 50ug PKSH031071
[Elabscience]
特徴
- 背景：Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has been shown that the transcription factor ATF2 is bound by a hetero-oligomer of Smad3 and Smad4 upon TGF-β stimulation. Studies indicate that ATF-2 plays a central role in TGF-β signaling by acting as a common nuclear target of both Smad and TAK1 pathways.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P15336-1
- タグ種類：N-His & GST
- アミノ酸配列：Met 1-Ser 505
- 遺伝子構造：A DNA sequence encoding full length of human ATF2 (P15336-1) (Met 1-Ser 505) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 別名（遺伝子名）：CRE-BP1;CREB-2;CREB2;HB16;TREB7
- 分子量：82.4 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% gly
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37670-Elabscience-PKSH031071.pdf
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89-7756-96
Recombinant Human ATF2 Protein (His & GST Tag) 100ug
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89-7756-95
Recombinant Human ATF2 Protein (His & GST Tag) 50ug
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