89-7756-93 ［取扱停止］Recombinant Human AKR1A1 Protein (His Tag) 20ug PKSH031070
[Elabscience]
特徴
- 背景：Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase. Aldehyde reductase has wide substrate specificities for carbonyl compounds. These enzymes are implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Aldehyde reductase possess a structure with a beta-alpha-beta fold which contains a novel NADP-binding motif. The binding site is located in a large, deep, elliptical pocket in the C-terminal end of the beta sheet, the substrate being bound in an extended conformation. This binding is more similar to FAD- than to NAD(P)-binding oxidoreductases. AKR1A1 is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P14550
- タグ種類：N-His
- アミノ酸配列：Met 1-Tyr 325
- 遺伝子構造：A DNA sequence encoding the human AKR1A1 (P14550) (Met 1-Tyr 325) was expressed, with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：ALDR1;ALR;ARM;DD3;HEL-S-6
- 分子量：39 kDa
- 組成：Lyophilized from sterile PBS, pH 7.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37669-Elabscience-PKSH031070.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7756-94
Recombinant Human AKR1A1 Protein (His Tag) 100ug
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89-7756-93
Recombinant Human AKR1A1 Protein (His Tag) 20ug
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