89-7756-82 Recombinant Human ALDH7A1/ATQ1 Protein (His Tag) 50ug PKSH031063
[Elabscience]
特徴
- 背景：ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 93 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P49419-2
- タグ種類：N-His
- アミノ酸配列：Ser 2-Gln 511
- 遺伝子構造：A DNA sequence encoding the human ALDH7A1 isoform 2 (P49419-2) (Ser 2-Gln 511) was expressed, with a polyhistide tag at the N-terminus.
- 別名（遺伝子名）：ATQ1;EPD;PDE
- 分子量：56 kDa
- 組成：Lyophilized from sterile 50mM Tris, 500mM NaCl, 20% glycerol, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37662-Elabscience-PKSH031063.pdf
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89-7756-81
Recombinant Human ALDH7A1/ATQ1 Protein (His Tag) 20ug
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89-7756-82
Recombinant Human ALDH7A1/ATQ1 Protein (His Tag) 50ug
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