89-7756-73 [取扱停止]Recombinant Human ALOX5AP/FLAP Protein (His Tag) 20ug PKSH031059
[Elabscience]特徴
- 背景:Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP), also known as FLAP, belongs to the MAPEG family. ALOX5AP/FLAP is an essential partner of 5-LO for this process. The FLAP (ALOX5AP) gene has been linked to risk for myocardial infarction, stroke and restenosis, reigniting pharmaceutical interest in this target. It had been found that ALOX5AP/FLAP is a key enzyme in leukotriene formation, in both human pulmonary microvascular endothelial cells and a transformed human brain endothelial cell line. In addition, the protein FLAP has recently been identified as an emerging target in metabolic disease. In fact, FLAP is overexpressed in the adipose tissue of patients and experimental animals with obesity.
仕様
- サイズ:20ug
- 種由来:Human
- 発現宿主:Baculovirus-Insect Cells
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:NP_001620.2
- タグ種類:C-His
- アミノ酸配列:Met 1-Pro 161
- 遺伝子構造:A DNA sequence encoding the full length of human ALOX5AP (NP_001620.2) (Met 1-Pro 161) was fused with a polyhistidine tag at the carboxy-terminus.
- 別名(遺伝子名):FLAP
- 分子量:19 kDa
- 組成:Lyophilized from sterile 20mM Tris, 150mM NaCl, 10% gly, pH 7.4, 0.5% triton, 5mM DTT
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-37658-Elabscience-PKSH031059.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7756-74
Recombinant Human ALOX5AP/FLAP Protein (His Tag) 100ug
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89-7756-73
Recombinant Human ALOX5AP/FLAP Protein (His Tag) 20ug
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