89-7756-69 ［取扱停止］Recombinant Human PCBP1 Protein (His Tag) 50ug PKSH031057
[Elabscience]
特徴
- 背景：Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. PCBP1 is widely expressed in many human tissues and involved in regulation of transcription, transportation process, and function of RNA molecules. PCBP1 plays a pivotal role in post-transcriptional regulation for RNA metabolism and RNA function in gene expression. PCBP1 acts as a negative regulator of CD44 variants splicing in HepG2 cells, and loss of PCBP1 in human hepatic tumor contributes to the formation of a metastatic phenotype.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 87 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_006187.2
- タグ種類：N-His
- アミノ酸配列：Asp 2-Cys 356
- 遺伝子構造：A DNA sequence encoding the human PCBP1 (NP_006187.2) (Asp 2-Cys 356) was expressed, with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：HEL-S-85;hnRNP-E1;hnRNP-X;HNRPE1;HNRPX
- 分子量：38.3 kDa
- 組成：Lyophilized from sterile 50mM Tris, 500mM NaCl, 20% glycerol, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37657-Elabscience-PKSH031057.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7756-69
Recombinant Human PCBP1 Protein (His Tag) 50ug
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89-7756-70
Recombinant Human PCBP1 Protein (His Tag) 100ug
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