89-7756-19 ［取扱停止］Recombinant Human NTPDase 2/ENTPD2 Protein (aa 29-460, His Tag)(Active) 10ug PKSH031019
[Elabscience]
特徴
- 背景：NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii infection. In L. pneumophila it was demonstrated that an E-NTPDase, similar to CD39, is essential for intracellular bacterial multiplication. NTPDase 2 is an integral membrane protein. In the nervous system, it could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Alternative splicing of NTPDase 2 gene results in multiple transcript variants.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q9Y5L3
- タグ種類：N-His
- アミノ酸配列：Thr 29-Asp460
- 遺伝子構造：A DNA sequence encoding the mature form of human ENTPD2 (Q9Y5L3) (Thr29-Asp460) was expressed, with a polyhistidine tag at the N-terminus.
- 活性：Measured by its ability to hydrolyze the 5’phosphate groups from the substrate adenosine 5’triphosphate(ATP).The specific activity is > 5,000 pmoles/min/μg.
- 別名（遺伝子名）：CD39L1;NTPDase-2;RP11-229P13.11-001
- 分子量：49.3 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37638-Elabscience-PKSH031019.pdf
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89-7756-19
Recombinant Human NTPDase 2/ENTPD2 Protein (aa 29-460, His Tag)(Active) 10ug
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89-7756-20
Recombinant Human NTPDase 2/ENTPD2 Protein (aa 29-460, His Tag)(Active) 20ug
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