89-7756-10 Recombinant Human IL17RC Protein (Fc Tag)(Active) 100ug PKSH031013
[Elabscience]
特徴
- 背景：Plexin domain-containing protein 1; also known as tumor endothelial marker 3; tumor endothelial marker 7 and PLXDC1 and TEM3; is a secreted; cytoplasm and single-pass type I membrane protein which belongs to the plexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer; and in endothelial cells from primary cancers of the lung; liver; pancreas; breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_116121.2
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Ala 454
- 遺伝子構造：A DNA sequence encoding the extracellular domain of human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with the Fc region of human IgG1 at the C-terminus.
- 活性：Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA.2. Measured by its ability to bind with recombinant human 17A in a functional ELISA.
- 別名（遺伝子名）：IL17-RL;IL17RL;UNQ6118/PRO20040/PRO38901
- 分子量：75.3 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37635-Elabscience-PKSH031013.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7756-10
Recombinant Human IL17RC Protein (Fc Tag)(Active) 100ug
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89-7756-09
Recombinant Human IL17RC Protein (Fc Tag)(Active) 50ug
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