89-7755-80 ［取扱停止］Recombinant Human STXBP3/UNC-18C Protein (His & GST Tag) 20ug PKSH030996
[Elabscience]
特徴
- 背景：Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STXBP3 participates in the consolidation and secretion of secondary and tertiary granules. STXBP3 contains one SEC1 domain. Phosphorylation at Ser129 may stimulate granule release. Human STXBP3 shares 90% aa identity with mouse STXBP3. STXBP3 interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion. Interacts with STX4.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 82 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：O00186-1
- タグ種類：N-His & GST
- アミノ酸配列：Met 1-Glu 592
- 遺伝子構造：A DNA sequence encoding the human STXBP3 (O00186-1) (Met 1-Glu 592) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 別名（遺伝子名）：MUNC18-3;MUNC18C;PSP;UNC-18C
- 分子量：95.6 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37627-Elabscience-PKSH030996.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7755-80
Recombinant Human STXBP3/UNC-18C Protein (His & GST Tag) 20ug
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89-7755-81
Recombinant Human STXBP3/UNC-18C Protein (His & GST Tag) 100ug
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