89-7755-76 ［取扱停止］Recombinant Human Semaphorin 4D/SEMA4D Protein (His Tag)(Active) 20ug PKSH030994
[Elabscience]
特徴
- 背景：SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 92 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q92854-1
- タグ種類：C-His
- アミノ酸配列：Met 1-Arg 734
- 遺伝子構造：A DNA sequence encoding the human SEMA4D isoform 1 (Q92854-1) extracellular domain (Met 1-Arg 734) was expressed, with a polyhistidine tag at the C-terminus.
- 活性：Measured by its binding ability in a functional ELISA. Immobilized human SEMA4D-His at 10 μg/ml (100 μl/well) can bind mouse PTPRC-Fc with a linear range of 0.625-5 μg/ml.
- 別名（遺伝子名）：Semaphorin-4D; A8;BB18; GR3; CD100;C9orf164;CD100;coll-4;M-sema-G;SEMAJ
- 分子量：80.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37625-Elabscience-PKSH030994.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7755-77
Recombinant Human Semaphorin 4D/SEMA4D Protein (His Tag)(Active) 50ug
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89-7755-76
Recombinant Human Semaphorin 4D/SEMA4D Protein (His Tag)(Active) 20ug
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