89-7755-55 Recombinant Human Caspase-14/CASP14 Protein (His Tag)(Active) 50ug PKSH030982
[Elabscience]
特徴
- 背景：Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_036246.1
- タグ種類：N-His
- アミノ酸配列：Ser 2-Gln 242
- 遺伝子構造：A DNA sequence encoding the human CASP14 (NP_036246.1) (Ser 2-Gln 242) was expressed, with a polyhistide tag at the N-terminus.
- 活性：Measured by its ability to bind biotinylated Cynomolgus IL18 in a functional ELISA.
- 別名（遺伝子名）：Caspase-14; CASP-14; CASP14;MGC119078;MGC119079
- 分子量：28.5 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105500-Elabscience-PKSH030982.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7755-55
Recombinant Human Caspase-14/CASP14 Protein (His Tag)(Active) 50ug
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89-7755-54
Recombinant Human Caspase-14/CASP14 Protein (His Tag)(Active) 20ug
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