89-7755-27 Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein (His Tag) 50ug PKSH030968
[Elabscience]
特徴
- 背景：Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme which belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 contains one ACT domain. Tryptophan hydroxylase catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. TPH1 expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells.The tryptophan hydroxylase 1 (TPH1) gene is also reported to be associated with suicidal behavior. Polymorphisms of TPH1 may assist in identifying a subgroup of mood disorder patients that is at higher risk for suicidal behavior.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P17752-1
- タグ種類：N-His
- アミノ酸配列：Ile 2-Ile 444
- 遺伝子構造：A DNA sequence encoding the human TPH1 (P17752-1) (Ile 2-Ile 444) was expressed, with a polyhistide tag at the N-terminus.
- 別名（遺伝子名）：TPRH;TRPH
- 分子量：52.7 kDa
- 組成：Lyophilized from sterile 20mM Tris, 200mM NaCl, 10% glycerol, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37603-Elabscience-PKSH030968.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7755-26
Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein (His Tag) 20ug
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89-7755-27
Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein (His Tag) 50ug
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