89-7754-45 ［取扱停止］Recombinant Human VWC2/Brorin Protein (His Tag) 50ug PKSH030918
[Elabscience]
特徴
- 背景：Brorin; also known as brain-specific chordin-like protein; von Willebrand factor C domain-containing protein 2 and VWC2; is a secreted protein which contains two VWFC domains. VWC2 / Brorin is a BMP antagonist which may play a role in neural development. It promotes cell adhesion. VWC2 / Brorin is a unique member of the chordin family. It inhibited the activity of bone morphogenetic protein 2 (BMP2) and BMP6 in mouse preosteoblastic MC3T3-E1 cells. Mouse Brorin was predominantly expressed in neural tissues in embryos and also predominantly expressed in the adult brain. In the brain; the expression was detected in neurons; but not glial cells. The neural tissue-specific expression profile of Brorin is quite distinct from that of any other member of the Chordin family. VWC2 / Brorin protein promoted neurogenesis; but not astrogenesis; in mouse neural precursor cells. VWC2 / Brorin is a novel secreted BMP antagonist that potentially plays roles in neural development and functions.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_940972.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Met 325
- 遺伝子構造：A DNA sequence encoding the human VWC2 (NP_940972.2) (Met 1-Met 325) was expressed; fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：PSST739;UNQ739
- 分子量：34.1 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37570-Elabscience-PKSH030918.pdf
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89-7754-46
Recombinant Human VWC2/Brorin Protein (His Tag) 100ug
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89-7754-45
Recombinant Human VWC2/Brorin Protein (His Tag) 50ug
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