89-7754-18 Recombinant Human FABP4/A-FABP Protein (29 Ala/Thr, His Tag) 100ug PKSH030902
[Elabscience]
特徴
- 背景：Fatty acid-binding protein; adipocyte; also known as Adipocyte-type fatty acid-binding protein; Fatty acid-binding protein 4; Adipocyte lipid-binding protein; and FABP4; is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL); FABP4 correlated to body mass index (BMI); waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index; triglycerides; HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD; adjusted by age; sex; body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients; and therefore; could serve to guide therapeutic intervention in this group of patients.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P15090
- タグ種類：N-His
- アミノ酸配列：Cys 2-Ala 132
- 遺伝子構造：A DNA sequence encoding the human FABP4 (P15090) (Cys 2-Ala 132) (29 Ala / Thr) was expressed; with a polyhistide tag at the N-terminus.
- 別名（遺伝子名）：Fatty Acid-Binding Protein Adipocyte; Adipocyte Lipid-Binding Protein; ALBP; Adipocyte-Type Fatty Acid-Binding Protein; A-FABP; AFABP; Fatty Acid-Binding Protein 4; aP2;HEL-S-104
- 分子量：16 kDa
- 組成：Lyophilized from sterile 50mM Tris; 200mM NaCl; 10% glycerol; pH 8.2
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105483-Elabscience-PKSH030902.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7754-17
Recombinant Human FABP4/A-FABP Protein (29 Ala/Thr, His Tag) 50ug
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89-7754-18
Recombinant Human FABP4/A-FABP Protein (29 Ala/Thr, His Tag) 100ug
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