特徴
- 背景：Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 92 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：Q01469
- アミノ酸配列：Met 1-Glu 135
- 遺伝子構造：A DNA sequence encoding the human FABP5 (Q01469) (Met 1-Glu 135) was expressed and purified.
- 別名（遺伝子名）：Fatty Acid-Binding Protein Epidermal; Epidermal-Type Fatty Acid-Binding Protein; E-FABP; Fatty Acid-Binding Protein 5; Psoriasis-Associated Fatty Acid-Binding Protein Homolog; PA-FABP; FABP5
- 分子量：15.2 kDa
- 組成：Lyophilized from sterile 50mM Tris; pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37495-Elabscience-PKSH030810.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7752-68
Recombinant Human FABP5 Protein 50ug
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89-7752-69
Recombinant Human FABP5 Protein 100ug
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