89-7752-62 ［取扱停止］Recombinant Human CD93/C1QR1 Protein (Fc Tag) 20ug PKSH030807
[Elabscience]
特徴
- 背景：CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes; neutrophils; endothelial cells; and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR; a receptor expressed during early B-cell development; is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive; memory; and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells; including long-lived plasma cells that showed decreased cell cycle activity; high levels of isotype-switched Ig secretion; and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q9NPY3
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Lys 580
- 遺伝子構造：A DNA sequence encoding the human CD93 (Q9NPY3) extracellular domain (Met 1-Lys 580) was fused with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：Complement Component C1q Receptor; C1q/MBL/SPA Receptor; C1qR; C1qR(p); C1qRp; CDw93; Complement Component 1 q Subcomponent Receptor 1; Matrix-Remodeling-Associated Protein 4CD93; C1QR1; MXRA4
- 分子量：85.2 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37493-Elabscience-PKSH030807.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7752-63
Recombinant Human CD93/C1QR1 Protein (Fc Tag) 50ug
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89-7752-62
Recombinant Human CD93/C1QR1 Protein (Fc Tag) 20ug
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