89-7752-10 ［取扱停止］Recombinant Human ALDH4A1 Protein (His & GST Tag) 20ug PKSH030776
[Elabscience]
特徴
- 背景：ALDH4A1 is a member of the aldehyde dehydrogenase family. Aldehyde dehydrogenase enzymes function in the metabolism of many molecules including certain fats (cholesterol and other fatty acids) and protein building blocks (amino acids). Additional aldehyde dehydrogenase enzymes detoxify external substances, such as alcohol and pollutants, and internal substances, such as toxins that are formed within cells. ALDH4A1 is expressed abundantly in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas. It is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 80 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：AAH07581.1
- タグ種類：N-His & GST
- アミノ酸配列：Lys 25-Gln 563
- 遺伝子構造：A DNA sequence encoding the mature form of human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 別名（遺伝子名）：ALDH4;P5CD;P5CDh
- 分子量：86.8 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37466-Elabscience-PKSH030776.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7752-10
Recombinant Human ALDH4A1 Protein (His & GST Tag) 20ug
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89-7752-11
Recombinant Human ALDH4A1 Protein (His & GST Tag) 100ug
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