89-7751-85 ［取扱停止］Recombinant Human SerpinB4 Protein (His Tag) 20ug PKSH030762
[Elabscience]
特徴
- 背景：Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in two forms: mitochondrial uracil-DNA glycosylase 1 (UNG1) and nuclear uracil-DNA glycosylase 2 (UNG2). uracil-DNA glycosylase. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 88 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：P48594
- タグ種類：N-His
- アミノ酸配列：Met 1-Pro 390
- 遺伝子構造：A DNA sequence encoding the human SERPINB4 (P48594) (Met 1-Pro 390) was expressed, with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：LEUPIN;PI11;SCCA-2;SCCA1;SCCA2
- 分子量：47.1 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 20% gly, 1mM EDTA, 1mM DTT
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105445-Elabscience-PKSH030762.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7751-85
Recombinant Human SerpinB4 Protein (His Tag) 20ug
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89-7751-86
Recombinant Human SerpinB4 Protein (His Tag) 50ug
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