89-7751-55 [取扱停止]Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag) 20ug PKSH030743
[Elabscience]特徴
- 背景:TSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone; in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.
仕様
- サイズ:20ug
- 種由来:Human
- 発現宿主:HEK293 Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:O60635
- タグ種類:N-Fc
- アミノ酸配列:Tyr110-Asn211
- 遺伝子構造:A DNA sequence encoding the human TSPAN1 (O60635)(Tyr110-Asn211) was expressed with the Fc region of rabbit IgG at the N-terminus.
- 別名(遺伝子名):NET1;TM4C;TM4SF;TSPAN1
- 分子量:39.1 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-37445-Elabscience-PKSH030743.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7751-56
Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag) 100ug
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89-7751-55
Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag) 20ug
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