89-7751-28 Recombinant Human PRL-2/PTP4A2 Protein (GST Tag) 100ug PKSH030728
[Elabscience]
特徴
- 背景：PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeutic targets. PRL-1, PRL-2, and PRL-3 represent a novel class of protein-tyrosine phosphatase with a C-terminal prenylation motif. They are three closely related intracellular enzymes that possess the PTP active site signature sequence CX 5R. The PRL-2 mRNA is elevated in primary breast tumors relative to matched normal tissue, and also dramatically elevated in metastatic lymph nodes compared with primary tumors. PRL-2 plays a role in breast cancer progression. PRL-2 is a pathogenic molecule in hematopoietic malignancies and suggest its potential as a novel therapeutic target.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：Q12974-1
- タグ種類：N-GST
- アミノ酸配列：Asn 2-Gln 167
- 遺伝子構造：A DNA sequence encoding the human PTP4A2 isoform 1 (Q12974-1) (Asn 2-Gln 167) was fused with the GST tag at the N-terminus.
- 別名（遺伝子名）：Protein tyrosine phosphatase type IVA 2;PTP4A2;HU-PP-1;OV-1;PTP(CAAXII);Protein-tyrosine phosphatase 4a2;Protein-tyrosine phosphatase of regenerating liver 2;PRL-2;HH13;HH7-2;HMT;HNMT-S1;HNMT-S2;HU-PP-1;OV-1;PRL-2;PRL2;ptp-IV1a;ptp-IV1b;PTP4A;PTPCAAX2
- 分子量：45.9 kDa
- 組成：Lyophilized from sterile 50mM Tris, 0.15M NaCl, 1mM GSH, pH 7.3
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37434-Elabscience-PKSH030728.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7751-28
Recombinant Human PRL-2/PTP4A2 Protein (GST Tag) 100ug
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89-7751-27
Recombinant Human PRL-2/PTP4A2 Protein (GST Tag) 20ug
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