89-7751-08 Recombinant Human Mesothelin/MSLN Protein (His Tag) 100ug PKSH030718
[Elabscience]
特徴
- 背景：Megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised by several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells; mesotheliomas; and ovarian cancer; but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas; ovarian cancers; and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q13421-2
- タグ種類：C-His
- アミノ酸配列：Met 1-Arg286
- 遺伝子構造：A DNA sequence encoding the human MSLN (Q13421-2) (Met1-Arg286) was expressed with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein;CAK1; MPF; MSLN; SMR; CAK1; CAK1 antigen
- 分子量：28.2 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37427-Elabscience-PKSH030718.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7751-07
Recombinant Human Mesothelin/MSLN Protein (His Tag) 50ug
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89-7751-08
Recombinant Human Mesothelin/MSLN Protein (His Tag) 100ug
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