89-7751-01 ［取扱停止］Recombinant Human CD247/CD3-ZETA Protein (GST Tag) 50ug PKSH030713
[Elabscience]
特徴
- 背景：CD247, also known as CD3-ZETA, belongs to the CD3Z/FCER1G family. It contains 3 ITAM domains. As a -cell receptor zeta, CD247 forms the T-cell receptor-CD3 complex together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and –epsilon. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for CD247 gene. Defects in CD247 can cause immunodeficiency due to defect in CD3-zeta. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens. CD247 may play a role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 92 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P20963-1
- タグ種類：N-GST
- アミノ酸配列：Arg52-Arg164
- 遺伝子構造：A DNA sequence encoding the mature form of human CD247 (P20963-1) (Arg52-Arg164) was fused with the GST tag at the N-terminus.
- 別名（遺伝子名）：CD3-ZETA;CD3H;CD3Q;CD3Z;IMD25;T3Z;TCRZ
- 分子量：40.2 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37423-Elabscience-PKSH030713.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7751-01
Recombinant Human CD247/CD3-ZETA Protein (GST Tag) 50ug
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89-7751-02
Recombinant Human CD247/CD3-ZETA Protein (GST Tag) 100ug
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