89-7750-91 ［取扱停止］Recombinant Human STAT6 Protein (Baculovirus, His Tag) 200ug PKSH030708
[Elabscience]
特徴
- 背景：Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-?B and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggest that the direct interaction between Stat6 and NF-?B may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-?B.
仕様
- サイズ：200ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P42226-1
- タグ種類：C-His
- アミノ酸配列：Met 1-Trp 847
- 遺伝子構造：A DNA sequence encoding the human STAT6 isoform 1 (P42226-1) (Met 1-Trp 847) was fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：Signal Transducer and Activator of Transcription 6; IL-4 Stat; STAT6;IL-4-STAT;STAT6B;STAT6C
- 分子量：95.5 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 20% gly, 0.3mM DTT
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37418-Elabscience-PKSH030708.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7750-90
Recombinant Human STAT6 Protein (Baculovirus, His Tag) 100ug
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89-7750-91
Recombinant Human STAT6 Protein (Baculovirus, His Tag) 200ug
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