89-7750-89 Recombinant Human Parathyroid Hormone/PTH Protein (aa 32-65, GST Tag) 100ug PKSH030707
[Elabscience]
特徴
- 背景：Parathyroid hormone (PTH); parathormone or parathyrin; is secreted by the chief cells of the parathyroid glands as a polypeptide. PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone (PTH) has been proved to play a pivotal role in maintaining myocardial contractility as well as effective natriuresis; and possible pathogenic mechanisms contributing to heart failure secondary to hypocalcemia and hypoparathyroidism. With the increased population of preosteoblastic lineages and the osteoblastic activation; Parathyroid hormone (PTH) drives anabolism in bone. Experiments have recently reported that PTH affects bone cells in a dual pathway - mediating osteoblastic (preosteoblastic) activities or osteocytic synthesis of sclerostin. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures; tetany and cramps.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 96 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P01270
- タグ種類：N-GST
- アミノ酸配列：Ser 32-Phe 65
- 遺伝子構造：A DNA sequence encoding the human PTH (P05062) (Ser 32-Phe 65) was fused with the GST tag at the N-terminus.
- 別名（遺伝子名）：Parathyroid Hormone; PTH; Parathormone; Parathyrin;PTH1
- 分子量：31 kDa
- 組成：Lyophilized from sterile PBS; pH 7.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37417-Elabscience-PKSH030707.pdf
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89-7750-88
Recombinant Human Parathyroid Hormone/PTH Protein (aa 32-65, GST Tag) 50ug
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89-7750-89
Recombinant Human Parathyroid Hormone/PTH Protein (aa 32-65, GST Tag) 100ug
|
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