89-7750-63 Recombinant Human TRP1/TYRP1 Protein (Human Cells, His Tag) 50ug PKSH030692
[Elabscience]
特徴
- 背景：Tyrosinase-related protein 1; also known as TYRP1 or TRP1; is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5;6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5;6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis; TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P17643
- タグ種類：C-His
- アミノ酸配列：Met 1- Arg 471
- 遺伝子構造：A DNA sequence encoding the human TYRP1 (P17643) extracellular domain (Met 1- Arg 471) was fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：b-PROTEIN;CAS2;CATB;GP75;OCA3;TRP;TRP1;TYRP
- 分子量：52.2 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37404-Elabscience-PKSH030692.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7750-63
Recombinant Human TRP1/TYRP1 Protein (Human Cells, His Tag) 50ug
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89-7750-62
Recombinant Human TRP1/TYRP1 Protein (Human Cells, His Tag) 20ug
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