89-7750-59 Recombinant Human Alkaline Phosphatase/ALPI Protein (His Tag)(Active) 50ug PKSH030690
[Elabscience]
特徴
- 背景：ALPI encodes for intestinal phosphatase alkaline; a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activity. ALPI mutations impaired either stability or catalytic activity of ALPI and rendered it unable to detoxify lipopolysaccharide-dependent signalling. ALPI mutations should be included in screening for monogenic causes of inflammatory bowel diseases and lay the groundwork for ALPI-based treatments in intestinal inflammatory disorders.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：P09923
- タグ種類：C-His
- アミノ酸配列：Met 1-Asp 503
- 遺伝子構造：A DNA sequence encoding the mature form of human ALPI (P09923) (Met 1-Asp 503);without the pro peptide; was fused with a polyhistidine tag at the C-terminus.
- 活性：Measured by its ability to cleave a fluorogenic substrate; 4-Methylumbelliferyl phosphate (4-MUP).The specific activity is > 1;000 pmoles/min/μg.
- 別名（遺伝子名）：IAP
- 分子量：54 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105429-Elabscience-PKSH030690.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7750-59
Recombinant Human Alkaline Phosphatase/ALPI Protein (His Tag)(Active) 50ug
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89-7750-58
Recombinant Human Alkaline Phosphatase/ALPI Protein (His Tag)(Active) 20ug
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