89-7750-13 Recombinant Human CALCB Protein (aa 1-118, Fc Tag) 100ug PKSH030665
[Elabscience]
特徴
- 背景：CALCB; also known as CGPR and calcitonin 2; belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin; blood; and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS); of monkeys infected with simian immunodeficiency virus; and of rats subjected to L5/L6 spinal nerve ligation; sciatic nerve chronic constriction; and subcutaneous injection of complete Freund's adjuvant. Increased CGRP-IL was also detected in epidermal keratinocytes of transgenic mice with keratin-14 promoter driven overexpression of noggin; an antagonist to BMP-4 signaling. CGPR dilates a variety of vessels including the coronary; cerebral and systemic vasculature.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：P10092
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Phe118
- 遺伝子構造：A DNA sequence encoding the human CALCB (P10092) (Met1-Phe118) was fused with Fc region of mouse IgG at the C-terminus.
- 別名（遺伝子名）：Calcitonin gene-related peptide 2; CALC2; Beta-type CGRP; Calcitonin gene-related peptide II; CALCB
- 分子量：36.2 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105416-Elabscience-PKSH030665.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7750-13
Recombinant Human CALCB Protein (aa 1-118, Fc Tag) 100ug
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89-7750-12
Recombinant Human CALCB Protein (aa 1-118, Fc Tag) 20ug
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