89-7750-05 ［取扱停止］Recombinant Human SIAE Protein (Baculovirus, His Tag) 20ug PKSH030659
[Elabscience]
特徴
- 背景：Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q9HAT2-1
- タグ種類：C-His
- アミノ酸配列：Met 1-Lys523
- 遺伝子構造：A DNA sequence encoding the human SIAE (Met 1-Lys523) (Q9HAT2-1) was expressed, with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：Sialate O-Acetylesterase; H-Lse; Sialic Acid-Specific 9-O-Acetylesterase; SIAE; YSG2;AIS6;CSE-C;CSEC
- 分子量：57.4 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105415-Elabscience-PKSH030659.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7750-05
Recombinant Human SIAE Protein (Baculovirus, His Tag) 20ug
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89-7750-04
Recombinant Human SIAE Protein (Baculovirus, His Tag) 10ug
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