89-7749-87 ［取扱停止］Recombinant Human TEM8/ATR Protein (Fc Tag) 20ug PKSH030646
[Elabscience]
特徴
- 背景：ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM); ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key proteins. ANTXR1 interacts with extracellular matrix proteins and with the actin cytoskeleton. It functions in cell attachment and migration. ANTXR1 also mediates adhesion of cells to type 1 collagen and gelatin; reorganization of the actin cytoskeleton and promotes cell spreading. It plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 92 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q9H6X2-4
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Ser321
- 遺伝子構造：A DNA sequence encoding the human ANTXR1 (Q9H6X2-4) (Met1-Ser321) was expressed; fused with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：Anthrax Toxin Receptor 1; Tumor Endothelial Marker 8; ANTXR1; ATR; TEM8
- 分子量：59.4 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37379-Elabscience-PKSH030646.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7749-88
Recombinant Human TEM8/ATR Protein (Fc Tag) 50ug
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89-7749-87
Recombinant Human TEM8/ATR Protein (Fc Tag) 20ug
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