89-7749-69 ［取扱停止］Recombinant Human BTN3A3 Protein (Fc Tag) 20ug PKSH030635
[Elabscience]
特徴
- 背景：Tumor necrosis factor receptor superfamily; member 19 (TNFRSF19); also known as TAJ-alpha or TROY; is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members; and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism; and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation; comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family; and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug of the protein as determined by the LAL method.
- アクセッションＮｏ．：O00478-1
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Trp248
- 遺伝子構造：A DNA sequence encoding the human BTN3A3 (O00478-1) (Met1-Trp248) was fused with Fc region of mouse IgG at the C-terminus.
- 別名（遺伝子名）：Butyrophilin subfamily 3 member A3;BTN3A3;BTF3;BTN3.3
- 分子量：50 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37369-Elabscience-PKSH030635.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7749-70
Recombinant Human BTN3A3 Protein (Fc Tag) 100ug
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89-7749-69
Recombinant Human BTN3A3 Protein (Fc Tag) 20ug
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