89-7749-64 Recombinant Human Jumping Translocation Breakpoint/JTB Protein (Fc Tag) 100ug PKSH030629
[Elabscience]
特徴
- 背景：Jumping translocation breakpoint, also known as JTB, is a member of the JTB family. Jumping translocation (JT) is an unbalanced translocation that comprises amplified chromosomalsegments jumping to various telomeres. JTB is expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts. It is required for normal cytokinesis during mitosis. JTB plays a role in the regulation of cell proliferation. It may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：O76095-1
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Leu105
- 遺伝子構造：A DNA sequence encoding the human JTB (O76095-1) (Met1-Leu105) was fused with Fc region of mouse IgG at the C-terminus.
- 別名（遺伝子名）：hJT;HJTB;HSPC222;JTB;PAR
- 分子量：34.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37366-Elabscience-PKSH030629.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7749-63
Recombinant Human Jumping Translocation Breakpoint/JTB Protein (Fc Tag) 20ug
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89-7749-64
Recombinant Human Jumping Translocation Breakpoint/JTB Protein (Fc Tag) 100ug
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