89-7749-50 Recombinant Human DCX Protein (aa 45-150, GST Tag) 50ug PKSH030620
[Elabscience]
特徴
- 背景：DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. It may act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. DCX may in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. It may be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration. Defects in DCX are the cause of lissencephaly X-linked type 1 and subcortical band heterotopia X-linked.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 82 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：O43602-2
- タグ種類：N-GST
- アミノ酸配列：Ala 45-Val 150
- 遺伝子構造：A DNA sequence encoding the human DCX (O43602-2) N-terminal fragment (Ala 45-Val 150) was fused with the GST tag at the N-terminus.
- 別名（遺伝子名）：DBCN;DC;LISX;SCLH;XLIS
- 分子量：39.4 kDa
- 組成：Lyophilized from sterile 20mM Tris, 1mM DTT, 10% glycerol, pH 7.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105409-Elabscience-PKSH030620.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7749-49
Recombinant Human DCX Protein (aa 45-150, GST Tag) 20ug
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89-7749-50
Recombinant Human DCX Protein (aa 45-150, GST Tag) 50ug
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