89-7749-33 ［取扱停止］Recombinant Human SELM/Selenoprotein M Protein (His Tag) 20ug PKSH030612
[Elabscience]
特徴
- 背景：Selenoprotein M is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine M is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. Selenoprotein M May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. This protein is widely expressed and is highly expressed in brain. It is found in Cytoplasm, perinuclear region, Endoplasmic reticulum, Golgi apparatus. Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum. Experiments results have suggested that selenoprotein M may have an important role in protecting against oxidative damage in the brain and may potentially function in calcium regulation.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：Q8WWX9
- タグ種類：C-His
- アミノ酸配列：Ala 24-Leu 145
- 遺伝子構造：A DNA sequence encoding the mature form of human SELM (Q8WWX9) (Ala 24-Leu 145) was fused with a polyhistidine tag at the C-terminus and an initial Met at the N-terminus.
- 別名（遺伝子名）：SEPM
- 分子量：15.4kDa
- 組成：Lyophilized from sterile 50mM Tris, 50mM NaCl, 50mM Arg, 0.3% Tween 20, 5% glycerol, pH 8.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37353-Elabscience-PKSH030612.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7749-33
Recombinant Human SELM/Selenoprotein M Protein (His Tag) 20ug
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89-7749-34
Recombinant Human SELM/Selenoprotein M Protein (His Tag) 100ug
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