89-7749-18 Recombinant Human ILT6/LILRA3 Protein (Fc Tag) 100ug PKSH030602
[Elabscience]
特徴
- 背景：ILT6, also known as LILRA3, belongs to the ILT family. In human, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 80 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：AAH28208.1
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Glu439
- 遺伝子構造：A DNA sequence encoding the human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：Leukocyte immunoglobulin-like receptor subfamily A member 3; CD85 antigen-like family member E; Immunoglobulin-like transcript 6; ILT-6; Leukocyte immunoglobulin-like receptor 4; LIR-4 and Monocyte inhibitory receptor HM43/HM31;CD85e;HM31;HM43;ILT6;LIR-4;LIR4
- 分子量：72 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105405-Elabscience-PKSH030602.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7749-17
Recombinant Human ILT6/LILRA3 Protein (Fc Tag) 50ug
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89-7749-18
Recombinant Human ILT6/LILRA3 Protein (Fc Tag) 100ug
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