89-7749-03 ［取扱停止］Recombinant Human NCKIPSD/SPIN90 Protein (GST Tag) 20ug PKSH030589
[Elabscience]
特徴
- 背景：NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. NCKIPSD also plays an important role in stress fiber formation. NCKIPSD gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified. NCKIPSD is a SH3 domain protein. Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins. Several previously described Fas ligand-interacting SH3 domain proteins turned out to be crucial for the regulation of storage, expression and function of the death factor. Recent observations, however, indicate that Fas ligand is also subject to posttranslational modifications including shedding and intramembrane proteolysis.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：Q9NZQ3-3
- タグ種類：N-GST
- アミノ酸配列：Met 1-Thr 244
- 遺伝子構造：A DNA sequence encoding the mature form of human NCKIPSD (Q9NZQ3-3) (Met1-Thr244) was expressed with the GST tag at the N-terminus.
- 別名（遺伝子名）：AF3P21;DIP;DIP1;ORF1;SPIN90;VIP54;WASLBP;WISH
- 分子量：53.2 kDa
- 組成：Lyophilized from sterile PBS, pH7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37338-Elabscience-PKSH030589.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7749-03
Recombinant Human NCKIPSD/SPIN90 Protein (GST Tag) 20ug
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89-7749-04
Recombinant Human NCKIPSD/SPIN90 Protein (GST Tag) 100ug
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