89-7747-95 ［取扱停止］Recombinant Human BBOX1/Gamma-BBH Protein (His & GST Tag) 20ug PKSH030526
[Elabscience]
特徴
- 背景：BBOX1, also known as gamma-BBH, belongs to the gamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. BBOX1 is an inhibition target for mildronate which can be used to treat angina andmyocardial infarction. Mildronate may also be beneficial for the treatment ofneurological disorder, diabetes, and seizures and alcohol intoxication.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：O75936
- タグ種類：N-His & GST
- アミノ酸配列：Met 1-Asn387
- 遺伝子構造：A DNA sequence encoding the human BBOX1 (O75936) (Met1-Asn387) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 別名（遺伝子名）：BBH;BBOX;G-BBH;gamma-BBH
- 分子量：72.5 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-37296-Elabscience-PKSH030526.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7747-96
Recombinant Human BBOX1/Gamma-BBH Protein (His & GST Tag) 100ug
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89-7747-95
Recombinant Human BBOX1/Gamma-BBH Protein (His & GST Tag) 20ug
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